Background: The review is a comprehensive overview of targets of antidiabetic interest and molecules that are reported to possess modulatory effects on glucose homeostasis.Drugs available in the market to treat diabetes restore blood glucose levels to normal, but are associated with undesirable effects.This has compelled the investigators to search
The role of nonalcoholic fatty liver disease, namely nonalcoholic steatohepatitis (NASH), as risk factor for liver- and non-liver-related morbidity and mortality has been extensively reported.In addition to lifestyle changes, capable of removing the metabolic factors driving disease progression, there is an urgent need for drugs able to reduce hepa
Stellate ganglia within the intrathoracic cardiac control system receive and integrate central, peripheral, and cardiopulmonary information to produce postganglionic cardiac sympathetic inputs.Pathological anatomical and structural remodeling occurs within the neurons of the stellate ganglion (SG) in the setting of heart failure (HF).A large propor